Calcitonin (CALCA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against α-CGRP. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu- Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val- Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2, (Disulfide bond) coupled to carrier protein.
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	calcitonin related polypeptide alpha
Database Link	Entrez Gene 796 Human UniProt ID P06881
Background	α-Calcitonin Gene-Related Peptide (α-CGRP) is a regulatory neuropeptide of 37 amino acids and is formed by the alternative splicing of the calcitonin / CGRP gene located on chromosome 11. It is widely distributed in both the peripheral and central nervous system, predominantly in cell bodies of the dorsal root ganglion (DRG) and it is known to be a potent vasodilator with inotropic and chronotropic effects. This antibody was generated by immunization of rabbits with α-Calcitonin Gene- Related Peptide coupled to a carrier protein.
Synonyms	CALC1; CGRP; CGRP-I; CGRP1; CT; katacalcin; KC; MGC126648; PCT; Procalcitonin
Reference Data

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