ANP (NPPA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against β-ANF (1- 28) (Dimer, Antiparallel). Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met- Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond linked dimer) coupled to a carrier protein.
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	natriuretic peptide A
Database Link	Entrez Gene 4878 Human UniProt ID P01160
Background	Atrial Natriuretic Factor (ANF) is a 28 amino acid peptide hormone secreted mainly by the heart atria in response to atrial stretch. ANF acts on the kidney to increase sodium excretion and glomerular filtration rate (GFR), to antagonize renal vasoconstriction, and to inhibit renin secretion. In addition, Atrial Natriuretic Factor consists of Atrial Natriuretic Peptide (ANP) which exists in its precursor form, pro- ANP and it is an active ANP with a longer peptide chain (Urodilatin) and an antiparallel dimer of active ANP: This antibody was generated by immunization of rabbits with β-Atrial Natriuretic Factor (1-28) (Dimer, Antiparallel) coupled to a carrier protein.
Synonyms	ANF; ANP; ATFB6; atriopeptin; cardionatrin; CDD-ANF; PND; prepronatriodilatin
Reference Data

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