Peptide YY (PYY) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Peptide YY. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala- Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu- Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2 coupled to a carrier protein.
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	peptide YY
Database Link	Entrez Gene 5697 Human UniProt ID P10082
Background	Peptide YY (PYY), also known as peptide tyrosine tyrosine, is a 36-amino acid peptide related to the pancreatic polypeptide (PP) family, with 18 of its 36 amino acids located in the same positions as pancreatic polypeptide. The two major forms of peptide YY are PYY1-36 and PYY3-36, which have PP fold structural motifs. PYY is released from cells in the ileum and colon in response to feeding, and exerts its action through neuropeptide Y (NPY) receptors. It has been shown to reduce appetite and may suppress pancreatic secretion. This antibody was generated by immunization of rabbits with Peptide YY coupled to a carrier protein.
Synonyms	PYY-I; PYY1
Reference Data

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