CRP Mouse Monoclonal Antibody [Clone ID: PC1 Biotin]

Specifications

Product Data
Clone Name	PC1 Biotin
Applications	ELISA, IHC
Recommend Dilution	Tested for ELISA and Western Blot. Approximate working dilutions: ELISA: 0.5µg/ml Western Blot: 1µg/ml Optimal dilutions should be determined by the end user.
Reactivity	Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified porcine CRP
Specificity	Pig: CRP Other species: not yet tested. Epitope: Porcine CRP, The epitope has not been characterized
Formulation	Affinity purified, biotinylated, lyophilized. Reconstitute by adding 0.5ml distilled water. This stock solution contains 0.5mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA) as a stabilizer and 0.05% (v/v) Kathon CG as a preservative.
Concentration	N/A
Conjugation	Biotin
Storage Condition	Original vial: 6 months at 4° - 8°C, 1 year at -20°C. Avoid repeated thawing and freezing.
Database Link	UniProt ID O19062
Background	Monoclonal antibody PC1 recognizes porcine C-reactive protein (CRP). CRP belongs to a highly conserved phylogenetically ancient family called pentraxins, which have five identical non-covalently linked subunits. Native CRP in its pentameric form has a molecular weight of approximately 115kDa. As in humans, CRP is an acute-phase protein in pigs. It has been suspected to be directly involved in the pathogenesis of ischemic diseases through the activation of the complement system. CRP levels have been measured in porcine serum. Median levels in specific pathogen-free animals were 5µg/ml and increased 40- to 70-fold due to inflammation or infection with Mycoplasma hyopneumoniae. Monoclonal antibody PC1 was generated against purified porcine CRP. This antibody was produced serum-free, without fetal calf serum.
Synonyms	MGC88244; MGC149895; PTX1
Reference Data

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