Cd200 Rat Monoclonal Antibody [Clone ID: OX-90]

Specifications

Product Data
Clone Name	OX-90
Applications	ELISA, IHC
Recommend Dilution	Tested for immunohistochemistry (IHC); has been described to work in FACS and ELISA.. Approximate working dilution for IHC: Frozen sections: 0.5µg/ml (1:800) Paraffin sections: does not react on routinely processed paraffin sections. Optimal dilutions should be determined by the end user. Suggested positive control: Mouse spleen.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Recombinant mouse CD200 (extracellular region)-rat CD4 (domains 3 & 4) fusion protein.
Specificity	Mouse: CD200 positive cells Other species: not tested Epitope: The epitope has not been further characterized. Distribution: Tissue Sections: The antigen is expressed on CD200 positive cells including thymocytes, some T cells, endothelial and follicular dendritic cells, and brain tissue (neurons).
Formulation	Affinity purified, lyophilized Reconstitute by adding 0.5ml distilled water. This stock solution contains 0.4mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA) as a stabilizer and 0.09% sodium azide as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: 1 year at 4° - 8°C. Stock solution or aliquots thereof: 1 year at -20°C. Avoid repeated thawing and freezing.
Gene Name	CD200 antigen
Database Link	Entrez Gene 17470 Mouse UniProt ID O54901
Background	Monoclonal antibody OX-90 reacts with CD200 (OX-2 antigen), a type-1 membrane glycoprotein containing two extracellular Ig-like domains. The molecular weight of the OX-2 antigen is 41 to 47kDa. CD200 is expressed on thymocytes, neurons, B lymphocytes, splenic follicular dendritic cells and endothelium, and subsets of T lymphocytes and dendritic cells: The antigen is not expressed on NK cells, granulocytes, monocytes or macrophages. The CD200 receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in the activation of anti-inflammatory pathways and the induction of immune tolerance.
Synonyms	CD200R1; MOX1; MOX2; MOX2R; MRC; OX-2; OX2R
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.