CEBP Alpha (CEBPA) Rabbit Polyclonal Antibody
CN¥ 4,628.00
货期*
2周
规格
经常一起买 (2)
Specifications
Product Data | |
Applications | WB |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPA |
Specificity | Expected reactivity: Cow, Guinea Pig, Human, Mouse, Pig, Rat Homology: Cow: 100%; Guinea Pig: 90%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100% |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage Condition | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Predicted Protein Size | 38kDa |
Gene Name | CCAAT/enhancer binding protein alpha |
Database Link | |
Background | CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. |
Synonyms | C/EBP-alpha; CEBP |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Acute myeloid leukemia, Pathways in cancer |
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