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CEBP Alpha (CEBPA) Rabbit Polyclonal Antibody
CNY 4,628.00
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CNY 3,080.00
CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | WB |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPA |
| Specificity | Expected reactivity: Cow, Guinea Pig, Human, Mouse, Pig, Rat Homology: Cow: 100%; Guinea Pig: 90%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100% |
| Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage Condition | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Predicted Protein Size | 38kDa |
| Gene Name | CCAAT/enhancer binding protein alpha |
| Database Link | |
| Background | CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. |
| Synonyms | C/EBP-alpha; CEBP |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | Acute myeloid leukemia, Pathways in cancer |
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