Psen2 Rabbit Polyclonal Antibody

CAT#: TA363683

PSEN2 Antibody - middle region



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CNY 4,628.00


货期*
2周

规格
    • 50 ug

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Specifications

Product Data
Applications WB
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Immunogen The immunogen is a synthetic peptide directed towards the middle region of mouse PSEN2
Specificity Expected reactivity: Mouse
Formulation Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Note that this product is shipped as lyophilized powder to China customers.
Concentration lot specific
Purification Affinity purified
Conjugation Unconjugated
Storage Condition For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size 50 kDa
Gene Name presenilin 2
Background This gene encodes a member of the presenilin family. Presenilins are catalytic components of the multi-subunit gamma-secretase complex, which mediates critical cellular processes through cleavage of type I transmembrane proteins including Notch receptors and the amyloid precursor protein. The encoded protein contains eight transmembrane domains and is localized to the endoplasmic reticulum, where it may play a role in calcium homeostasis. Following assembly of the gamma-secretase complex, the encoded protein is cleaved into N- and C-terminal fragments and the activated complex is released from the endoplasmic reticulum. Inactivation of this gene results in impaired synaptic function in a mouse model for Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. 
Synonyms AD3L; AD3LP; AD4; AD5; E5-1; PS-2; PS2; PSNL2; STM-2; STM2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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