CD32B (FCGR2B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the middle terminal region of Human FCGR2C
Specificity	Expected reactivity: Human
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	35 kDa
Gene Name	Fc fragment of IgG receptor IIb
Database Link	NP_963857.3 Entrez Gene 9103 HumanEntrez Gene 2213 Human UniProt ID P31995
Background	The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Synonyms	CD32; CD32B; CDw32; Fc-gamma-RIIb; FCG2; FCGR2; FcRII-b; IGFR2
Reference Data
Protein Families	ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus

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