IKAP (IKBKAP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the C-terminal region of human IKBKAP
Specificity	Expected reactivity: Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat Homology: Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	38kDa
Gene Name	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
Database Link	NP_003631.2 Entrez Gene 8518 Human UniProt ID O95163
Background	The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms	DKFZp781H1425; DYS; ELP1; FD; FLJ12497; IKAP; IKI3; p150; TOT1
Reference Data
Protein Families	Druggable Genome

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