SCD5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat, Sheep Homology: Cow: 93%; Dog: 92%; Guinea Pig: 79%; Horse: 92%; Human: 100%; Pig: 93%; Rabbit: 86%; Rat: 86%; Sheep: 93%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	37kDa
Gene Name	stearoyl-CoA desaturase 5
Database Link	NP_001032671 Entrez Gene 79966 Human UniProt ID Q86SK9
Background	Stearoyl-CoA desaturase is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates.
Synonyms	ACOD4; FADS4; FLJ21032; HSCD5; SCD2; SCD4
Reference Data
Protein Families	Transmembrane
Protein Pathways	Biosynthesis of unsaturated fatty acids, PPAR signaling pathway

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