NLRP3 Rabbit Polyclonal Antibody

Name: NLRP3 Rabbit Polyclonal Antibody
SKU: TA358397
Price: 5070.00

CAT＃: TA358397

NLRP3 Antibody - N-terminal region

Datasheet

SDS

Need it in bulk or conjugated?
Get a free quote

CNY 5,070.00

货期*

2周

规格

Cited in 1 publication.

Product images

经常一起买 (4)

LY401526

Transient overexpression lysate of NLR family, pyrin domain containing 3 (NLRP3), transcript variant 1

CNY 4,840.00

TA811000S

beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control

CNY 300.00
CNY 1,430.00

【特别福利】购一抗正装产品（≥50ul或≥50ug），免费领10ul抗体试用装

TP320952

Purified recombinant protein of Human NLR family, pyrin domain containing 3 (NLRP3), transcript variant 1, full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20 µg

CNY 2,900.00

TP320952M

Purified recombinant protein of Human NLR family, pyrin domain containing 3 (NLRP3), transcript variant 1, full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 100 µg

CNY 9,998.00

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	Expected reactivity: Cow, Dog, Horse, Human, Pig, Rabbit Homology: Cow: 93%; Dog: 79%; Horse: 93%; Human: 100%; Pig: 93%; Rabbit: 79%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	114kDa
Gene Name	NLR family, pyrin domain containing 3
Database Link	NP_004886 Entrez Gene 114548 Human UniProt ID Q96P20
Background	This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID).
Synonyms	AGTAVPRL; AII; AII/AVP; AVP; C1orf7; CIAS1; CLR1.1; cryopyrin; FCAS; FCU; FLJ95925; MWS; NALP3; PYPAF1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	NOD-like receptor signaling pathway

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

The use of this Antibodies has been cited in the following citations:
Thioredoxin-interacting protein: a potential therapeutic target for treatment of progressive fibrosis in diabetic nephropathy. ,null, Nephron ,PubMed ID 25662516 [NLRP3]

Documents

Product Manuals
Development Guilde Goat anti-Mouse IgG [H&L] Western Blotting Luminol Kit
FAQs
Antibody and Western Standard
SDS
Antibody SDS

Resources

抗体相关资料
Product Overview Video: UltraMAB Product Overview Video: TrueMAB Webinar Recording: UltraMAB Video Tutorial: Video Tutorial: Antibody specificity and Knockout(KO) lysates Western Blot Protocol IHC Protocol IF Protocol FACS Protocol Immunoprecipitation (IP) Protocol IP protocol with magnetic beads

其它NLRP3产品

Expression Plasmids

Lentiviral Particles

CRISPR

RNAi

Proteins

Antibodies