OGG1 Rabbit Polyclonal Antibody
CNY 4,628.00
CNY 300.00
CNY 1,430.00
CNY 3,080.00
CNY 3,080.00
Specifications
Product Data | |
Applications | WB |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Specificity | Directed against isoforms 2D, 1A, 1B, 2E. Expected reactivity: Cow, Dog, Horse, Human, Mouse, Pig, Rat Homology: Cow: 93%; Dog: 100%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 92%; Rat: 79% |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage Condition | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Predicted Protein Size | 38kDa |
Gene Name | 8-oxoguanine DNA glycosylase |
Database Link | |
Background | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. |
Synonyms | HMMH; HOGG1; MMH; MUTM; OGH1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Base excision repair |
Documents
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Resources
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