Tyrosinase (TYR) Mouse Monoclonal Antibody [Clone ID: T311]

Specifications

Product Data
Clone Name	T311
Applications	IHC
Recommend Dilution	1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant prokaryotic protein corresponding to the tyrosinase molecule
Specificity	Human tyrosinase
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	tyrosinase
Database Link	Entrez Gene 7299 Human UniProt ID P14679
Background	The biosynthesis of melanin in melanocytes involves a family of enzymes, a key member of which is tyrosinase. Tyrosinase deficiency is associated with various forms of albinism and in particular oculocutaneous albinism. L-tyrosinase is the initial substrate for melanin biosynthesis and its conversion to dopaquinone is catalyzed by tyrosinase, whose expression is reported in melanocytes and melanomas.
Synonyms	LB24-AB; OCA1A; OCAIA; SHEP3; SK29-AB; tyrosinase
Reference Data

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