TdT (DNTT) Mouse Monoclonal Antibody [Clone ID: SEN28]

Specifications

Product Data
Clone Name	SEN28
Applications	IHC
Recommend Dilution	1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant protein corresponding to the amino terminal region of the terminal deoxynucleotidyl transferase molecule
Specificity	Human terminal deoxynucleotidyl transferase
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	DNA nucleotidylexotransferase
Database Link	Entrez Gene 1791 Human UniProt ID P04053
Background	Terminal deoxynucleotidyl transferase (TdT) is a DNA polymerase of 58 kD located in the cell nucleus which catalyzes the polymerization of deoxynucleotides at the 3' hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template. TdT is reported to be expressed in primitive T and B lymphocytes of the normal thymus and bone marrow. The identification of TdT-positive cell populations in primary and secondary lymphoid organs during maturation of the immune system is one area of interest but it is the reported occurrence of high levels of enzyme activity in white blood cells and bone marrow in certain leukemias which is of particular interest.
Synonyms	TDT
Reference Data

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