Myosin Heavy Chain (fast) Mouse Monoclonal Antibody [Clone ID: WB-MHCf]

Specifications

Product Data
Clone Name	WB-MHCf
Applications	IHC
Recommend Dilution	1:10 - 1:40
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Native myosin extracted from rabbit psoas muscle
Specificity	Rabbit myosin fast type heavy chain. Crossreacts with human myosin fast type heavy chain. The antibody also reacts with type II myosin heavy chain (both IIa and IIb) in rat, mouse, dog, sheep, pig and goat muscle
Formulation	Lyophilized tissue culture supernatant containing 15 mM sodium azide as a preservative.
Reconstitution Method	The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Background	Myosin is a contractile muscle specific protein composed of two heavy and four light chains. The myosin heavy chain has many isoforms which are specific for different muscles or fiber types, some of which are developmentally regulated. The range of myosin heavy chain antibodies may prove useful for investigating development of intrafusal and extrafusal muscle fibers and the course of muscle fiber regeneration. At the ultrastructural level, antibodies can reveal architectural details of the myofilament as well as the cytoplasmic and membrane sites of new myosin integration.
Reference Data

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