Her2 (ERBB2) Mouse Monoclonal Antibody [Clone ID: CB11]

Specifications

Product Data
Clone Name	CB11
Applications	IHC
Recommend Dilution	1:40
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide corresponding to a site on the internal domain of the human c-erbB-2 oncoprotein
Specificity	Human c-erbB-2 oncoprotein (internal domain). Specific binding has been demonstrated by immunoprecipitation with c-erbB-2 oncoprotein SKBR3 cells
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	erb-b2 receptor tyrosine kinase 2
Database Link	Entrez Gene 2064 Human UniProt ID P04626
Background	The c-erbB-2 oncoprotein is closely related in structure to the epidermal growth factor receptor and is a member of a large family of cell surface growth factor receptors. c-erbB-2 oncoprotein is reported to be detectable in a proportion of breast and other adenocarcinomas as well as transitional cell carcinomas. c-erbB-2 oncoprotein is present in a wide variety of cell types in a range of normal human fetal and adult tissues, including breast, stomach and ovary. CB11 detects the internal domain of the c-erbB-2 oncoprotein. CBE-356 detects the external domain of the c-erbB-2 oncoprotein.
Synonyms	C-erbB-2; CD340; erbB-2; HER-2; HER-2/neu; HER2; herstatin; NEU; NGL; p185erbB2; TKR1
Reference Data

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