CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: 10F11]

Specifications

Product Data
Clone Name	10F11
Applications	IHC
Recommend Dilution	1:80
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant protein corresponding to a region of the N-terminal intracellular domain of the human CD71 molecule
Specificity	Human CD71 molecule, also known as transferrin receptor
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	transferrin receptor
Database Link	Entrez Gene 7037 Human UniProt ID P02786
Background	The CD71 molecule is a type II membrane glycoprotein with a molecular weight of approximately 180 kD. It is known as the transferrin receptor and is composed of two disulfide-bonded 90 kD subunits. The CD71 molecule plays a critical role in cell proliferation by controlling the supply of iron, an essential component for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. CD71 protein is reported to be expressed on activated B and T cells, macrophages, proliferating cells and metabolically active cells, for example, neurons.
Synonyms	CD71; p90; T9; TfR; TfR1; TR; Trfr
Reference Data

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