CD21 (CR2) Mouse Monoclonal Antibody [Clone ID: 2G9]

Specifications

Product Data
Clone Name	2G9
Applications	IHC
Recommend Dilution	1:80
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant protein corresponding to the external domain of the human CD21 molecule
Specificity	Human CD21 molecule
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	complement component 3d receptor 2
Database Link	Entrez Gene 1380 Human UniProt ID P20023
Background	CD21 antigen is a type I integral membrane glycoprotein of molecular weight 140 kD, which functions as the receptor for the C3d fragment of the third complement component. The CD21 molecule, present on mature B cells, is involved in transmitting growth-promoting signals to the interior of the B cell and acts as a receptor for Epstein-Barr virus. CD21 antigen is reported to be found in B cell chronic lymphocytic leukemias and in a subset of T cell acute lymphocytic leukemias but is absent on T lymphocytes, monocytes and granulocytes. CD21 antigen is also reported to be expressed in follicular dendritic cells and in follicular and mantle cell lymphomas, mature leukemias and lymphomas.
Synonyms	C3DR; CD21; SLEB9
Reference Data

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