SARS-CoV-2 N Protein Rabbit Monoclonal Antibody [Clone ID: DM23]

Specifications

Product Data
Clone Name	DM23
Applications	ELISA
Recommend Dilution	ELISA 1/5000-1/10000
Reactivity	SARS-CoV-2
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant SARS-CoV-2 Nucleocapsid (Met1-Ala419) (TP723996) produced by using E. coli
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. Preservative: 0.1% Procline 300
Reconstitution Method	Reconstitute with deionized water
Purification	Purified from cell culture supernatant by affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Predicted Protein Size	45kDa
Database Link	Entrez Gene 43740575 SARS-CoV-2
Background	Coronavirus contain most of nucleocapsid protein. Coronavirus nucleoproteins (N proteins) localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The nucleolus is the site of ribosome biogenesis and sequesters cell cycle regulatory complexes. Two of the major components of the nucleolus are fibrillarin and nucleolin. These proteins are involved in nucleolar assembly and ribosome biogenesis and act as chaperones for the import of proteins into the nucleolus. Regarding of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is a tool for diagnostic.
Reference Data

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