alpha Tubulin (TUBA1A) Mouse Monoclonal Antibody [Clone ID: 2B11]

CAT#: TA355046

Mouse Monoclonal Anti-alpha-Tubulin Antibody [2B11]



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

Cited in 1 publication.

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Specifications

Product Data
Clone Name 2B11
Applications WB
Recommend Dilution WB: 1-2µg/ml.
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish
Host Mouse
Clonality Monoclonal
Immunogen alpha-Tubulin antibody was raised against an 18 amino acid peptide near the carboxy terminus of human alpha-Tubulin
Formulation alpha-Tubulin antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification alpha-Tubulin antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size Predicted: 50 kDa; Observed: 54 kDa
Gene Name tubulin alpha 1a
Background Alpha-Tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-Tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter (reviewed in 1). Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-Tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase (2). Another post-translational modification of detyrosinated alpha-Tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle (3). Like GAPDH and ?-Actin, this antibody makes an excellent loading control in immunoblots.
Synonyms B-ALPHA-1; FLJ25113; hum-a-tub1; hum-a-tub2; LIS3; TUBA3
Note alpha-Tubulin antibody can be used for detection of alpha-Tubulin by Western blot at 1 - 2 µg/ml.
Reference Data
Protein Families Druggable Genome
Protein Pathways Gap junction, Pathogenic Escherichia coli infection
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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