TRIM58 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1-2µg/mL.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	TRIM58 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TRIM58.
Formulation	TRIM58 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	TRIM58 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 53 kDa; Observed: 56 kDa
Gene Name	tripartite motif containing 58
Database Link	NP_056246 Entrez Gene 25893 Human UniProt ID Q8NG06
Background	TRIM58 Antibody: TRIM58 is a member of the tripartite motif-containing family of proteins that frequently possess E3 ubiquitin ligase activities (1). TRIM58 is strongly expressed in erythroid lineage cells and is further upregulated during late erythroid maturation. Recent experiments suggest that TRIM58 facilitates erythroblast enucleation by ubiquitinating the intermediate chain of the microtubule motor dynein, thereby inducing proteolytic degradation (2).
Synonyms	BIA2; DKFZp434C091
Note	TRIM58 antibody can be used for Western blot at 1 - 2 µg/mL.
Reference Data

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