E7 protein Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to the N-terminus of human papillomavirus type 16.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~N/A
Database Link	Entrez Gene 8223418
Background	The strain of Human papilloma virus 16 (HPV16 or E7 protein) is directly linked to cervical cancer and can be diagnosed with a colposcopy and biopsy. Human papilloma virus is one of the most common causes of sexually transmitted infection in the world. E7 protein has transforming and trans-activating activities that are known to disrupt the function of host retinoblastoma protein (Rb1). E6 is a transcriptional trans-activator with transforming activities targeting p53 tumor suppressor. HPV16, in comparison to HPV types 6 and 11, is more often associated with malignant genital cancers in humans. This antibody was raised in rabbit against protein E7 of human papillomavirus type 16 (HPV16) which is mainly used for research on sexually-transmitted diseases and gynecology tumors.
Reference Data

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