MEK5 (MAP2K5) Rabbit Polyclonal Antibody

CAT#: TA354845

Rabbit anti MAPKK5 (MEK5) (Paired S311/T315) Polyclonal Antibody



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CNY 4,675.00


货期*
5周

规格
    • 100 ug

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经常一起买 (2)
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Transient overexpression lysate of mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant A
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Specifications

Product Data
Applications Dot, WB
Recommend Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide surrounding the epitope –SIAKT- without any phosphorylation modification. This sequence is identical among human, rat, mouse, chicken, and dog.
Formulation This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 49 kDa
Gene Name mitogen-activated protein kinase kinase 5
Background The MEK5 (also known as MKK5, MAPKK5, SKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. It catalyzes tyrosine phosphorylation of ERK5 whereas MEK5 itself is regulated by MEKK3. An important link between MEK5 and metastatic prostrate cancer has been demonstrated. Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation.
Synonyms HsT17454; MAPKK5; MEK5; PRKMK5
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Gap junction, MAPK signaling pathway, Neurotrophin signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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