JAK2 Rabbit Polyclonal Antibody

CAT#: TA354828

Rabbit anti JAK2(pY1007/Y1008) Polyclonal Antibody



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CNY 4,675.00


货期*
5周

规格
    • 100 ug

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经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

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Recombinant protein of human Janus kinase 2 (a protein tyrosine kinase) (JAK2), 20 µg
    • 20 ug

CNY 2,900.00

Specifications

Product Data
Applications Dot, WB
Recommend Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide surrounding to the epitope -EYYK- with dual phosphorylation sites at Tyr1007 and Tyr1008 of JAK2 from human, mouse and rat origins
Formulation This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by site-modified Epitope Affinity Purification.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 120 kDa (130 kDa)
Gene Name Janus kinase 2
Background The Janus tyrosine kinase family is consists of four members, JAK1, JAK2, JAK3 and Tyk2. Upon the cytokine ligand binding to its the receptors, the dimerization of the receptors occurs followed by phosphorylation of the receptors. The phosphorylation of receptors recruites the tyrosine kinase physically associated to the dimerized receptors, and phosphorylate the kinase, thus activates the signal transducer and activator of thranscription (STAT1, 3, 5) and the other signal proteins.
Synonyms JTK10; THCYT3
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Adipocytokine signaling pathway, Chemokine signaling pathway, Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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