Corin Rabbit Polyclonal Antibody
CAT#: TA354723
Rabbit anti Corin (CT) Polyclonal Antibody
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CNY 4,675.00
货期*
5周
规格
经常一起买 (1)
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to the C-terminus of mouse corin protein. This sequence is identical to rat and human origins. |
Formulation | This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. |
Purification | The Rabbit IgG is purified by Epitope Affinity Purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | ~120 kDa |
Gene Name | corin |
Database Link | |
Background | Corin, is a glycosylated protease on the cell surface as a single pass type II membrane protein. It is located on trial and brain natriurectic peptides (ANP and NNP) expressing cell surfaces. It may occur in both zymogen and catlytically active forms. The multi-domain transmembrane serine protease corin cleaves pro-atrial natriuretic peptide (pro-ANP) in vitro to generate an active hormone, ANP at R123-S124. Corin is higher expressed on cardiomyocytes. It may also contribute to the regulation of the natriuretic peptide system in vivo, and might be an attractive target for treatment of cardiovascular diseases. |
Synonyms | ATC2; CRN; Lrp4; MGC119742; pro-ANP-convertase; PRSC; TMPRSS10 |
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