Thymidine Kinase 1 (TK1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Drosophila
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to the N-terminus of fruit fly thymidine kinase protein.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26 kDa
Gene Name	thymidine kinase 1
Database Link	NP_003249 Entrez Gene 7083 Human UniProt ID P04183
Background	Deoxynucleoside kinases (dNK) are key enzymes in deoxyribonucleoside salvage, activating several clinically important chemotherapeutic drugs. Deoxynulceoside kinases catalyze the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribocytidine kinase (dCK), deoxyriboguanosine kinase(dGK), cytosolic thymidine kinase(TK1) and mitochondrial thymidine kinase (TK2).
Synonyms	TK2
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

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