CD20 (MS4A1) Mouse Monoclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	A synthetic peptide corresponding to C-terminus of human CD20 protein.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34 kDa
Gene Name	membrane spanning 4-domains A1
Database Link	NP_068769 Entrez Gene 931 Human UniProt ID P11836
Background	CD20, a non-glycosylated protein, belongs to a member of the membrane-spanning 4A gene family. The molecular weight is at a range of ~34-37kDa depending on the degree of the protein phosphorylation. The CD20 antigen is present on human pre B lymphocytes and B lymphocytes at all stages of maturation. Thus, it plays an important role in the development and differentiation of B-cells into plasma cells. Low level of CD20 expression appears on normal T lymphocytes. Combination of chemo and humanized CD20 antibodies has been reported in clinical study of lymphoma diseases.
Synonyms	B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Hematopoietic cell lineage

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