Midkine (MDK) Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 143 aa recombinant protein of the full length human Midkine. This sequence has 90% homologues to rat and mouse.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	15 kDa
Gene Name	midkine (neurite growth-promoting factor 2)
Database Link	NP_001012333 Entrez Gene 4192 Human UniProt ID P21741
Background	Midkine is a member of a family of developmentally regulated neurotrophic and heparin-binding growth factors. It has heparin binding activity and growth promoting activity. The midkine is involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. This protein is also involved in early fetal adrenal gland development. Midkine may be an important skeletal muscle growth-promoting factor that participates in the growth process during skeletal muscle development, proliferation, and differentiation, and in the skeletal muscle regeneration in various neuromuscular disorders.
Synonyms	ARAP; MK; NEGF2
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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