Caspase 9 (CASP9) Rabbit Polyclonal Antibody

CAT#: TA354214

Rabbit anti Caspase 9 Polyclonal Antibody



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CNY 4,675.00


货期*
5周

规格
    • 100 ug

Product images

经常一起买 (3)
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Recombinant protein of human caspase 9, apoptosis-related cysteine peptidase (CASP9), transcript variant beta, 20 µg
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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide derived from N-terminus of human Caspase 9 protein
Formulation This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 47 kDa
Gene Name caspase 9
Background Caspase-9 belongs to a member of the cysteine-aspartic acid protease (Caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small. Those dimerize to form the active enzyme. Activation of procaspase-9 by Apaf-1 in the Cytochrome C/dATP-dependent pathway requires proteolytic cleavage to generate the mature caspase molecule. Once activated, caspase-9 can initiate a caspase cascade involving the downstream executioner caspase-3, -6 and -7.
Synonyms APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56
Reference Data
Protein Families Druggable Genome, Protease, Stem cell - Pluripotency
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Endometrial cancer, Huntington's disease, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Parkinson's disease, Pathways in cancer, Prostate cancer, Small cell lung cancer, VEGF signaling pathway, Viral myocarditis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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