TREM2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1000-5000 WB positive control: Mouse heart tissue, Human cerebella tissue, Human cerebrum tissue, Mouse liver tissue lysates
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human TREM2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25 kDa
Gene Name	triggering receptor expressed on myeloid cells 2
Database Link	NP_061838 Entrez Gene 83433 MouseEntrez Gene 54209 Human UniProt ID Q9NZC2
Background	This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
Synonyms	TREM-2; Trem2a; Trem2b; Trem2c
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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