HUNK Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human HUNK
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	hormonally up-regulated Neu-associated kinase
Database Link	NP_055401 Entrez Gene 30811 Human UniProt ID P57058
Background	The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker.
Synonyms	hormonally up-regulated Neu-associated kinase; hormonally upregulated Neu-associated kinase; hormonally upregulated neu tumor-associated kinase; OTTHUMP00000107427; serine; threonine protein kinase MAK-V
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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