TM7SF2 Rabbit Polyclonal Antibody
CAT#: TA351818S
Rabbit Polyclonal Anti-TM7SF2 Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
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CNY 3,080.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: Human fetal brain tissue IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human TM7SF2 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 46 kDa |
Gene Name | transmembrane 7 superfamily member 2 |
Database Link | |
Background | Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+. |
Synonyms | ANG1; DHCR14A; NET47 |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Metabolic pathways, Steroid biosynthesis |
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