TAP2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human TAP2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Database Link	NP_061313 Entrez Gene 21355 MouseEntrez Gene 24812 RatEntrez Gene 6891 Human UniProt ID Q03519
Background	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2.
Synonyms	ABC18; ABCB3; APT2; D6S217E; PSF-2; PSF2; RING11
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	ABC transporters, Antigen processing and presentation, Primary immunodeficiency

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