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RCC1 Rabbit Polyclonal Antibody
CAT＃: TA351589S
Rabbit Polyclonal Anti-RCC1 Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Jurkat, 293T, CNE2 and HUVEC cell lysates |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human RCC1 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 45 kDa |
| Gene Name | regulator of chromosome condensation 1 |
| Database Link | |
| Background | RCC1 (regulator of chromosome condensation 1), increases the rate at which Ran exchanges GDP for GTP. Ran GAP1 opposes the effects of RCC1 by increasing the rate at which Ran hydrolyzes GTP to GDP. A protein designated Ran BP1 has no intrinsic GAP activity and functions as a GEF inhibitor, deactivating RCC1 and thereby indirectly increasing the ratio of Ran GDP to Ran GTP. Ran BP2 has been proposed as the Ran GTP docking site at the periphery of the nuclear pore complex. |
| Synonyms | CHC1; RCC1-I; SNHG3-RCC1 |
| Reference Data | |
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