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PPM1F Rabbit Polyclonal Antibody
CAT＃: TA351551S
Rabbit Polyclonal Anti-PPM1F Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
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Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: K562 cells and human fetal liver tissue IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PPM1F |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 50 kDa |
| Gene Name | protein phosphatase, Mg2+/Mn2+ dependent 1F |
| Database Link | |
| Background | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. |
| Synonyms | CAMKP; CaMKPase; FEM-2; hFEM-2; POPX2 |
| Reference Data | |
| Protein Families | Druggable Genome, Phosphatase |
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