NDUFAB1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 100-300 Positive control: Human lung cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human NDUFAB1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	NADH:ubiquinone oxidoreductase subunit AB1
Database Link	NP_004994 Entrez Gene 4706 Human UniProt ID O14561
Background	NDUFAB1 (NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1), also known as SDAP, ACP (acyl carrier protein) or FASN2A, is one of about 45 subunits comprising Complex I of the oxidative phosphorylation electron transport chain. Consisting of 156 amino acids and localizing to mitochondria, NDUFAB1 functions as an accessory subunit of the multi-protein mitochondrial membrane respiratory chain NADH dehydrogenase complex (known as Complex I). Complex I plays an important role in the transfer of electrons from NADH to the respiratory chain, a process that is essential for cellular respiration. NDUFAB1 contains one acyl carrier domain and is encoded by a gene that maps to human chromosome 16p12.2 and mouse chromosome 7 F3.
Synonyms	ACP; FASN2A; SDAP
Reference Data
Protein Pathways	Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

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