NALP6 (NLRP6) Rabbit Polyclonal Antibody
CAT#: TA351426S
Rabbit Polyclonal Anti-NLRP6 Antibody
Size: 100 ul
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CNY 300.00
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CNY 4,840.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm and Nucleus |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human NLRP6 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | NLR family, pyrin domain containing 6 |
Database Link | |
Background | The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. |
Synonyms | AVR; CLR11.4; NALP6; NAVR; PAN3; PYPAF5 |
Reference Data |
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