SnoN (SKIL) Rabbit Polyclonal Antibody
CAT#: TA350435S
Rabbit Polyclonal Anti-SKIL Antibody
Size: 100 ul
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CN¥ 800.00
CN¥ 1,280.00
货期*
2周
规格
经常一起买 (2)
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 200-1000 WB positive control: Huvec cells IHC: 30-150 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human SKIL |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 77 kDa |
Gene Name | SKI-like proto-oncogene |
Database Link | |
Background | The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. |
Synonyms | SNO; SnoA; SnoI; SnoN |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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