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PTRH2 Rabbit Polyclonal Antibody
CAT＃: TA350314S
Rabbit Polyclonal Anti-PTRH2 Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 1000-5000 WB positive control: Raji, Jurkat, 231, hepg2 and K562 cells IHC: 10-50 Positive control: Human breast cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PTRH2 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 19 kDa |
| Gene Name | peptidyl-tRNA hydrolase 2 |
| Database Link | |
| Background | PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis. |
| Synonyms | BIT1; CFAP37; CGI-147; IMNEPD; PTH; PTH 2; PTH2 |
| Reference Data | |
| Protein Families | Transmembrane |
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