PTPMT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: Human fetal muscle tissue
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human PTPMT1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	23 kDa
Gene Name	protein tyrosine phosphatase, mitochondrial 1
Database Link	NP_783859 Entrez Gene 114971 Human UniProt ID Q8WUK0
Background	PTPMT1 (protein tyrosine phosphatase mitochondrial 1), also known as MOSP or PLIP (phosphoinositide lipid phosphatase) and previously known as DUSP23, is a widely expressed PTP membrane protein with high expression levels in pancreatic cells. PTPMT1 exclusively localizes to the matrix face of the inner membrane of the mitochondrion. It is responsible for dephosphorylating mitochondrial proteins and therefore plays a significant role in the production of ATP and secretion of insulin.
Synonyms	DUSP23; MOSP; PLIP; PNAS-129
Reference Data
Protein Families	Druggable Genome

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