Glucocorticoid Receptor (NR3C1) Rabbit Polyclonal Antibody
CAT#: TA350022S
Rabbit Polyclonal Anti-NR3C1 Antibody
Size: 100 ul
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CN¥ 800.00
CN¥ 1,280.00
货期*
2周
规格
经常一起买 (2)
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: K562, 231, Hela, HepG2 cell, Mouse liver tissue, A172 cell, Jurkat cell, Mouse smooth muscle cell lysates IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human NR3C1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 86 kDa |
Gene Name | nuclear receptor subfamily 3 group C member 1 |
Database Link | |
Background | This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. |
Synonyms | GCCR; GCR; GCRST; GR; GRL |
Reference Data | |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Protein Pathways | Neuroactive ligand-receptor interaction |
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