AIFM3 Rabbit Polyclonal Antibody
CAT#: TA349675S
Rabbit Polyclonal Anti-AIFM3 Antibody
Size: 100 ul
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CN¥ 800.00
CN¥ 1,280.00
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CN¥ 6,650.00
CN¥ 4,840.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 200-1000 WB positive control: Hela cells IHC: 50-200 Positive control: Human cervical cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human AIFM3 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 67 kDa |
Gene Name | apoptosis inducing factor, mitochondria associated 3 |
Database Link | |
Background | AIFL (apoptosis-inducing factor-like), also known as AIFM3 (apoptosis-inducing factor, mitochondrion-associated, 3), is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain. Expressed ubiquitously in tissues including liver, thymus, ovary, bone marrow and cerebral cortex, AIFL functions to induce apoptosis, specifically through a caspase-dependent pathway, and may also play a role in the modulation of mitochondrial membrane potential. Multiple isoforms of AIFL exist due to alternative splicing events. The gene encoding AIFL maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. |
Synonyms | AIFL |
Reference Data | |
Protein Families | Druggable Genome |
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