PIP5K3 (PIKFYVE) Rabbit Polyclonal Antibody
CAT#: TA349589S
Rabbit Polyclonal Anti-PIKFYV Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human PIKFYV |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | phosphoinositide kinase, FYVE-type zinc finger containing |
Database Link | |
Background | Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKFYVEe; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. |
Synonyms | CFD; FAB1; HEL37; PIP5K; PIP5K3; ZFYVE29 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis, Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, Regulation of actin cytoskeleton |
Documents
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