Sigma1 receptor (SIGMAR1) Rabbit Polyclonal Antibody
CAT#: TA349569S
Rabbit Polyclonal Anti-SIGMAR1 Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: Mouse liver and brain tissue, A549 cells IHC: 100-300 Positive control: Human gasrtic cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human SIGMAR1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 25 kDa |
Gene Name | sigma non-opioid intracellular receptor 1 |
Database Link | |
Background | This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. |
Synonyms | ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SR-BP; SR-BP1; SRBP |
Reference Data | |
Protein Families | Druggable Genome, GPCR, Transmembrane |
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