Prohibitin (PHB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: 293T and A549 cells, human hepatocellsular carcinoma tissue and PC3 cells,hela cells and mouse heart tissue IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human PHB
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	30 kDa
Gene Name	prohibitin
Database Link	NP_002625 Entrez Gene 18673 MouseEntrez Gene 25344 RatEntrez Gene 5245 Human UniProt ID P35232
Background	This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants
Synonyms	HEL-215; HEL-S-54e; PHB1
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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