ENT1 (SLC29A1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	SLC29A1 antibody was raised against a 17 amino acid peptide near the center of human SLC29A1.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	SLC29A1 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 50 kDa; Observed: 53 kDa
Gene Name	solute carrier family 29 member 1 (Augustine blood group)
Database Link	NP_004946 Entrez Gene 2030 Human UniProt ID Q99808
Background	SLC29A1 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A1 is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium (3). As a nucleoside transporter, SLC29A1 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4).
Synonyms	ENT1
Reference Data

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