WDR61 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	WDR61 antibody was raised against a 14 amino acid peptide near the amino terminus of human WDR61.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	WDR61 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 34 kDa; Observed: 30 kDa
Gene Name	WD repeat domain 61
Database Link	NP_079510 Entrez Gene 66317 MouseEntrez Gene 363064 RatEntrez Gene 80349 Human UniProt ID Q9GZS3
Background	WDR61 (WD-repeat-containing protein 61), also known as SKI8 or REC14, is a subunit of the human PAF and SKI complexes, which function in transcriptional regulation and are involved in events downstream of RNA synthesis, such as RNA surveillance (1,2). PAF1C is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1C (3,4).
Synonyms	REC14; SKI8
Reference Data
Protein Pathways	RNA degradation

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