CADM3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	CADM3 antibody was raised against a 16 amino acid peptide near the center of human CADM3.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	CADM3 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 44, 48 kDa; Observed: 44 kDa
Gene Name	cell adhesion molecule 3
Database Link	NP_067012 Entrez Gene 57863 Human UniProt ID Q8N126
Background	Cell adhesion molecule 3 (CADM3) is a member of a family of immunoglobulin-like, calcium-independent cell-cell adhesion molecules (1,2). CADM3 localizes to non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes and is thought to play an important role in the formation of synapses, axon bundles and myelinated axons (3). Recently, CADM3 has been shown to suppress the growth and tumorigenic ability of colon cancer cells, indicating that it can act as a tumor suppressor (4).
Synonyms	BIgR; IGSF4B; Necl-1; NECL1; synCAM3; TSLL1
Reference Data

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