Sex Hormone Binding Globulin (SHBG) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	SHBG antibody was raised against a 16 amino acid peptide near the center of human SHBG.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	SHBG antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Predicted Protein Size	Predicted: 25, 26, 31, 32, 38, 44 kDa; Observed: 35
Gene Name	sex hormone binding globulin
Database Link	NP_001031 Entrez Gene 20415 MouseEntrez Gene 24775 RatEntrez Gene 6462 Human UniProt ID P04278
Background	SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers (1). Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes (2,3). Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus (4).
Synonyms	ABP; SBP; TEBG
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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