SOX18 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	SOX18 antibody was raised against a 17 amino acid peptide near the amino terminus of human SOX18.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	SOX18 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 42 kDa; Observed: 44 kDa
Gene Name	SRY-box 18
Database Link	NP_060889 Entrez Gene 54345 Human UniProt ID P35713
Background	SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2). SOX18 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types (3). SOX is known to be involved with vascularization and endothelial development, suggesting that it may be useful as a potential target for inhibiting tumor angiogenesis (4). Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia (5).
Synonyms	EPLIN; SREBP3
Reference Data

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